- The Nobel Prize for Physiology or Medicine in 2013
- Investigator of the Howard Hughes Medical Institute
- Professor of Cell and Developmental Biology in the Department of Molecular and Cell Biology at the University of California at Berkeley
Dr. Randy Wayne Schekman is an American cell biologist at the University of California, Berkeley, who was elected to the National Academy of Sciences in 1992, and former editor-in-chief of Proceedings of the National Academy of Sciences. In 2011, he was announced as the editor of eLife, a new high-profile open-access journal published by the Howard Hughes Medical Institute, the Max Planck Society and the Wellcome Trust launched in 2012. Schekman shared the 2013 Nobel Prize for Physiology or Medicine with James Rothman and Thomas C. Südhof for their ground-breaking work on cell membrane vesicle trafficking.
The cells inside our bodies produce a host of different molecules that are sent to specific sites. During transport, many of these molecules are grouped together in tiny sac-like structures called vesicles. These vesicles help transport substances to different places inside the cell and send molecules from the cell's surface as signals to other cells in the body. During the 1970s, Randy Schekman studied yeast cells with malfunctions in this transportation system. He demonstrated that the malfunctions were due to genetic defects and explained how different genes regulate different aspects of the transports.
The Schekman Lab
Dr. Schekman owns his own biology lab. Here’s the link to the lab website: https://mcb.berkeley.edu/labs/schekman
The Schekman lab studies membrane assembly, vesicular transport, and membrane fusion among organelles of the secretory pathway. Basic principles that emerged from our past studies in yeast are now being applied to studies of genetic diseases of protein transport, as well to the study of extracellular vesicles.